lol - just went through this same problem... I use a maximized screen setting, or I should say used to. It took some getting used to but I forced myself back to how the rest of the world sees the internet.
1024 X 768 is the most used screen resolution:
You can do a quick google search for all these kinds of things - most used browser, version, screen resolution...
The truth of the matter really lies in your own stats... Every niche market holds a different kind of internet user. If your creating a technical blog, chances are your "customers" are going to be savvy surfers...
If you don't have a site up already I would say go web standard 1024 x 768
Then once you have gotten a good deal of traffic from multiple sources, it would be a good idea to take a tally of your web traffic stats to see what your users use for browsers and screen resolutions.