What are your best color layout which gives you the most click? I always go with the white back ground. It seem to work very well.

Use a white background ...it works best. If you go to like colorful and stuff the ads would seem weird because most normal ads are white and people won't click ads if their diff colors.

I think the color scheme that match to website will do well.

I customize my color scheme so that it fits in with whatever site I'm working on. It fits into the site better than simple white ads. Looks classier, too.

Sometimes using colors that stands out can help also. Yes it depends on your site mate.

I have studied this and if you want to not annoy the visitors and do want some good clicks, make it blend in with your website. BUT if you need alot of clicks quickly, make it yellow and red, like yellow background, red typing or otherway around! this increases the clicks a lot! It's a marketing trick