I was wondering if anyone in the community is using devs like Joomla or OSCommerce for building their sites? Also if there are any better options out there. Help Appreciated...

I've had clients who use OSCommerce, but lately most of the people I know are developing e-commerce solutions in-house.

Zen Cart for sure.

90% of my clients use:
oscommerce
zencart
cubecart(if you can find a version < 4.0)

But if you are a developer I would recommend building your own.
Here is a half-way decent tutorial and foundation script to work with:
http://www.phpwebcommerce.com/
note: you'll have to do a lot of modifications but it's a good start.

I am a 100% support of Oscommerce, it is great with lots of templates to use and lots of mods to add.

i am supporting zencart and virtual mart for e-commerce site .
i think zen-cart is best opensource